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lobotomy (n.)

1936, coined from lobe (in the brain sense) + medical suffix -tomy "a cutting." Figurative use is attested from 1953. Lobectomy (attested from 1911) was in use earlier in reference to lobes of other organs (lungs, liver).

Now I guess I'll have to tell 'em
That I got no cerebellum
[Ramones, "Teenage Lobotomy," 1977]

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Definitions of lobotomy from WordNet

lobotomy (n.)
surgical interruption of nerve tracts to and from the frontal lobe of the brain; often results in marked cognitive and personality changes;
Synonyms: leukotomy / leucotomy / prefrontal lobotomy / prefrontal leukotomy / prefrontal leucotomy / frontal lobotomy
From wordnet.princeton.edu