Old English læs (adv.) "less, lest;" læssa (adj.) "less, smaller, fewer" (Northumbrian leassa), from Proto-Germanic *laisizan (source also of Old Saxon, Old Frisian les "less;" Middle Dutch lise "soft, gentle," German leise "soft"), from PIE root *leis- (2) "small" (source also of Lithuanian liesas "thin") + comparative suffix.
From the first, the adverb has been used often with negatives (none the less). Much less "still more undesirable" is from 1630s. Formerly also "younger," as a translation of Latin minor, a sense now obsolete except in James the Less. Used as a comparative of little, but not related to it. The noun is Old English læsse.
word-forming element making verbs (such as darken, weaken) from adjectives or nouns, from Old English -nian, from Proto-Germanic *-inojan (also source of Old Norse -na), from PIE adjectival suffix *-no-. Most active in Middle English and early modern English, hence most verbs in -en are comparatively recent.
<a href="https://www.etymonline.com/word/lessen">Etymology of lessen by etymonline</a>
Harper, D. (n.d.). Etymology of lessen. Online Etymology Dictionary. Retrieved $(datetime), from https://www.etymonline.com/word/lessen