Etymology
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lesion (n.)

early 15c., "damage, injury," from Old French lesion "hurt, offense, wrong, injury, wound" (12c.), from Latin laesionem (nominative laesio) "a hurting, injuring, personal attack," noun of action from past participle stem of laedere "to strike, hurt, damage," a word of unknown origin with no certain cognates. Originally in English with reference to any sort of hurt, whether physical or not.

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Definitions of lesion

lesion (n.)
any localized abnormal structural change in a bodily part;
lesion (n.)
an injury to living tissue (especially an injury involving a cut or break in the skin);
Synonyms: wound
From wordnet.princeton.edu