Etymology
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isolation (n.)

1800, noun of action from isolate (v.) or else from French isolation, noun of action from isoler (see isolated).

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Definitions of isolation

isolation (n.)
a state of separation between persons or groups;
isolation (n.)
a feeling of being disliked and alone;
isolation (n.)
the act of isolating something; setting something apart from others;
Synonyms: closing off
isolation (n.)
(psychiatry) a defense mechanism in which memory of an unacceptable act or impulse is separated from the emotion originally associated with it;
isolation (n.)
a country's withdrawal from international politics;
he opposed a policy of American isolation
From wordnet.princeton.edu