Etymology
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instruction (n.)

c. 1400, instruccioun, "action or process of teaching," from Old French instruccion (14c., Modern French instruction), from Latin instructionem (nominative instructio) "an array, arrangement," in Late Latin "teaching," from past participle stem of instruere "arrange, prepare, set in order; inform, teach," from in- "on" (from PIE root *en "in") + struere "to pile, build" (from PIE *streu-, extended form of root *stere- "to spread").

Teaching is the general word for the imparting of knowledge .... Instruction has the imparting of knowledge for its object, but emphasizes, more than teaching, the employment of orderly arrangement in the things taught. [Century Dictionary]

Meaning "an authoritative direction telling someone what to do; a document giving such directions," is early 15c. Related: Instructions.

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Definitions of instruction

instruction (n.)
a message describing how something is to be done;
Synonyms: direction
instruction (n.)
the activities of educating or instructing; activities that impart knowledge or skill;
our instruction was carefully programmed
Synonyms: education / teaching / pedagogy / didactics / educational activity
instruction (n.)
the profession of a teacher;
Synonyms: teaching / pedagogy
instruction (n.)
(computer science) a line of code written as part of a computer program;
Synonyms: command / statement / program line
From wordnet.princeton.edu