Etymology
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imprecation (n.)

mid-15c., "a curse, cursing," from Latin imprecationem (nominative imprecatio) "an invoking of evil," noun of action from past participle stem of imprecari "invoke, pray, call down upon," from assimilated form of in- "into, in, within" (from PIE root *en "in") + precari "to pray, ask, beg, request" (from PIE root *prek- "to ask, entreat"). "Current limited sense is characteristic of human nature" [Weekley].

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Definitions of imprecation

imprecation (n.)
the act of calling down a curse that invokes evil (and usually serves as an insult);
he suffered the imprecations of the mob
Synonyms: malediction
imprecation (n.)
a slanderous accusation;
From wordnet.princeton.edu