early 15c., "unchanging, unalterable," from Old French immutable (Modern French immuable), and directly from Latin immutabilis "unchangeable, unalterable," from assimilated form of in- "not, opposite of" (see in- (1)) + mutabilis "changeable," from mutare "to change" (from PIE root *mei- (1) "to change, go, move"). Related: Immutably.
