Etymology
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ho (interj.)

exclamation of surprise, etc., c. 1300; as an exclamation calling attention or demanding silence, late 14c. Used after the name of a place to which attention is called (as in Westward-Ho) it dates from 1590s, originally a cry of boatmen, etc., announcing departures for a particular destination. Ho-ho-ho expressing laughter is recorded from mid-12c.

ho (n.)

by 1993, American English slang, representing an African-American vernacular pronunciation of whore.

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Definitions of ho
1
ho (n.)
binary compound that occurs at room temperature as a clear colorless odorless tasteless liquid; freezes into ice below 0 degrees centigrade and boils above 100 degrees centigrade; widely used as a solvent;
Synonyms: water
2
Ho (n.)
a trivalent metallic element of the rare earth group; occurs together with yttrium; forms highly magnetic compounds;
Synonyms: holmium / atomic number "
From wordnet.princeton.edu