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high-strung (adj.)

also high strung, 1848 in the figurative sense, "having a sensitive nervous system," from high (adv.) + strung. In literal use a musical term, in reference to stringed instruments, attested from 1748.

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Definitions of high-strung from WordNet

high-strung (adj.)
being in a tense state;
Synonyms: edgy / highly strung / jittery / jumpy / nervy / overstrung / restive / uptight
From wordnet.princeton.edu