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heartsick (adj.)

also heart-sick, "despondent," late 14c., from heart (n.) + sick (adj.). Old English heortseoc meant "ill from heart disease."

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Definitions of heartsick

heartsick (adj.)
full of sorrow;
Synonyms: brokenhearted / heartbroken
heartsick (adj.)
without or almost without hope;
too heartsick to fight back
Synonyms: despondent
From wordnet.princeton.edu