Etymology
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heartbreak (n.)

also heart-break, "overwhelming grief or sorrow," 1570s, from heart (n.) + break (n.). Expression break (someone's) heart is from c. 1400. Related: Heartbreaking.

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Definitions of heartbreak

heartbreak (n.)
intense sorrow caused by loss of a loved one (especially by death);
Synonyms: grief / heartache / brokenheartedness
From wordnet.princeton.edu