Etymology
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grinder (n.)

Old English grindere "one who grinds (grain);" agent noun from grind (v.). Meaning "molar tooth" is late 14c. (Old English had grindetoð). Meaning "machine for milling" is from 1660s; of persons, from late 15c. "Large sandwich" sense is from 1954, American English, though the exact signification is uncertain (perhaps from the amount of chewing required to eat one).

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Definitions of grinder

grinder (n.)
a large sandwich made of a long crusty roll split lengthwise and filled with meats and cheese (and tomato and onion and lettuce and condiments); different names are used in different sections of the United States;
Synonyms: bomber / hero / hero sandwich / hoagie / hoagy / Cuban sandwich / Italian sandwich / poor boy / sub / submarine / submarine sandwich / torpedo / wedge / zep
grinder (n.)
grinding tooth with a broad crown; located behind the premolars;
Synonyms: molar
grinder (n.)
machinery that processes materials by grinding or crushing;
Synonyms: mill / milling machinery
grinder (n.)
a machine tool that polishes metal;
From wordnet.princeton.edu