Etymology
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go off (v.)

1570s, of firearms, etc., "explode, be discharged;" see go (v.) + off (adv.); meaning "depart" is c. 1600; that of "deteriorate in condition" is from 1690s; that of "reprimand" is from 1941 (originally with at, since c. 2000 more often with on).

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Definitions of go off

go off (v.)
run away; usually includes taking something or somebody along;
Synonyms: abscond / bolt / absquatulate / decamp / run off / make off
go off (v.)
be discharged or activated;
go off (v.)
go off or discharge;
Synonyms: fire / discharge
go off (v.)
stop running, functioning, or operating;
go off (v.)
happen in a particular manner;
Synonyms: come off / go over
go off (v.)
burst inward;
Synonyms: implode
From wordnet.princeton.edu