Etymology
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fretful (adj.)

1590s, "gnawing; disposed to fret," from fret (n.) (see fret (v.)) + -ful. Related: Fretfully; fretfulness.

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Definitions of fretful

fretful (adj.)
nervous and unable to relax;
a constant fretful stamping of hooves
Synonyms: antsy / fidgety / itchy
fretful (adj.)
habitually complaining;
Synonyms: querulous / whiney / whiny
From wordnet.princeton.edu