Etymology
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femur (n.)

1560s, at first in English as an architectural term; 1799 as "thighbone;" from Latin femur "thigh, upper part of the thigh," which is of unknown origin.

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Definitions of femur

femur (n.)
the longest and thickest bone of the human skeleton; extends from the pelvis to the knee;
Synonyms: thighbone / femoris
From wordnet.princeton.edu