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exterminate (v.)

1540s, "drive away," from Latin exterminatus, past participle of exterminare "drive out, expel, put aside, drive beyond boundaries," also, in Late Latin "destroy," from phrase ex termine "beyond the boundary," from ex "out of" (see ex-) + termine, ablative of termen "boundary, limit, end" (see terminus).

Meaning "destroy utterly" is from 1640s in English, a sense found in equivalent words in French and in the Vulgate; earlier in this sense was extermine (mid-15c.). Related: Exterminated; exterminating.

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Definitions of exterminate from WordNet

exterminate (v.)
kill en masse; kill on a large scale; kill many;
Hitler wanted to exterminate the Jews, Gypsies, Communists, and homosexuals of Europe
Synonyms: kill off
exterminate (v.)
destroy completely, as if down to the roots;
Synonyms: uproot / eradicate / extirpate / root out
From wordnet.princeton.edu