Etymology
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exasperation (n.)

"irritation, provocation," 1540s, from Late Latin exasperationem (nominative exasperatio), noun of action from past-participle stem of exasperare "roughen; irritate" (see exasperate).

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Definitions of exasperation

exasperation (n.)
an exasperated feeling of annoyance;
Synonyms: aggravation
exasperation (n.)
actions that cause great irritation (or even anger);
From wordnet.princeton.edu