1570s, from French epilepsie (16c.), from Late Latin epilepsia, from Greek epilepsis "epilepsy," literally "a seizure," from epilambanein "to lay hold of, seize upon, attack," especially of diseases, but also of events, armies, etc., from epi "upon" (see epi-) + lepsis "seizure," from leps-, future stem of lambanein "take hold of, grasp" (see lemma). Earlier was epilencie (late 14c.), from French epilence, a variant form influenced by pestilence. The native name in English was falling sickness.