emasculate (v.)

mid-14c., "belonging to the male grammatical gender;" late 14c., "of men, of male sex," from Old French masculin "of the male sex" (12c.), from Latin masculinus "male, of masculine gender," from masculus "male, masculine; worthy of a man," diminutive of mas (genitive maris) "male person, male," a word of unknown origin. The diminutive form might be by pairing association with femininus (see feminine). Meaning "having the appropriate qualities of the male sex, physically or mentally: Manly, virile, powerful" is attested by 1620s. As a noun, "masculine gender," from c. 1500.

"the act of depriving a male of the function which characterizes the sex; castration," also more generally "the act of depriving of vigor or strength," 1620s, noun of action from emasculate.