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elephantiasis (n.)

1580s, from Greek elephantos, genitive of elephas "elephant" (see elephant) + -iasis "pathological or morbid condition." It refers to two diseases, one characterized by thickening of a body part (E. Arabum), the other, older meaning is "disease characterized by skin resembling an elephant's" (E. Græcorum, also called Egyptian leprosy). In Middle English, elephancy (late 14c.).

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Definitions of elephantiasis from WordNet

elephantiasis (n.)
hypertrophy of certain body parts (usually legs and scrotum); the end state of the disease filariasis;
From wordnet.princeton.edu