Etymology
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DOS

"computer operating system using a disk storage device," 1967, acronym of disk operating system.

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Definitions of DOS
1
dos (n.)
an operating system that is on a disk;
Synonyms: disk operating system
2
DoS (n.)
the federal department in the United States that sets and maintains foreign policies;
Synonyms: Department of State / United States Department of State / State Department / State
From wordnet.princeton.edu