late 15c. (Caxton), "destroy or derange the order of, throw into confusion," from dis- "not" (see dis-) + order (v.). Replaced earlier disordeine (mid-14c.), from Old French desordainer, from Medieval Latin disordinare "throw into disorder," from Latin dis- + ordinare "to order, regulate," from ordo (genitive ordinis) "row, rank, series, arrangement" (see order (n.)). Related: Disordered; disordering.
1520s, "lack of regular arrangement;" 1530s, "tumult, disturbance of the peace;" from disorder (v.). Meaning "an ailment, a disturbance of the body or mind" is by 1704.