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disaffect (v.)

1620s, "lack affection for" (a sense now obsolete); 1640s, "alienate the affection of, make less friendly" (the main modern sense), from dis- + affect (v.1). Related: Disaffected; disaffecting.

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Definitions of disaffect from WordNet

disaffect (v.)
arouse hostility or indifference in where there had formerly been love, affection, or friendliness;
Synonyms: estrange / alienate
From wordnet.princeton.edu