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derangement (n.)

1737, "disturbance of regular order," from French dérangement (17c.), from déranger (see derange). Mental sense "disturbance of the intellect or reason" is from 1800.

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Definitions of derangement from WordNet

derangement (n.)
a state of mental disturbance and disorientation;
Synonyms: mental unsoundness / unbalance
derangement (n.)
the act of disturbing the mind or body;
Synonyms: upset / overthrow
From wordnet.princeton.edu