derail (v.)

active word-forming element in English and in many verbs inherited from French and Latin, from Latin de "down, down from, from, off; concerning" (see de), also used as a prefix in Latin, usually meaning "down, off, away, from among, down from," but also "down to the bottom, totally" hence "completely" (intensive or completive), which is its sense in many English words.

As a Latin prefix it also had the function of undoing or reversing a verb's action, and hence it came to be used as a pure privative — "not, do the opposite of, undo" — which is its primary function as a living prefix in English, as in defrost (1895), defuse (1943), de-escalate (1964), etc. In some cases, a reduced form of dis-.

"horizontal bar passing from one post or support to another," c. 1300, from Old French raille, reille "bolt, bar," from Vulgar Latin *regla, from Latin regula "rule, straight piece of wood," diminutive form related to regere "to straighten, guide" (from PIE root *reg- "move in a straight line").

 In U.S. use, "A piece of timber, cleft, hewed, or sawed, inserted in upright posts for fencing" [Webster, 1830]. Used figuratively for thinness from 1872. By 1830s as "iron or steel bar or beam used on a railroad to support and guide the wheels." To be off the rails "out of the normal or proper condition" in a figurative sense is from 1848, an image from railroads.

"act of derailing or causing to leave the rails," 1850, from French déraillement, from dérailler "to go off the rails" (see derail).