Etymology
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depression (n.)

c. 1400 as a term in astronomy, "angular distance of a star below the horizon," from Old French depression (14c.) and directly from Medieval Latin depressionem (nominative depressio), noun of action from past participle stem of Latin deprimere "to press down, depress" (see depress).

The literal sense "act of pressing down, state of being pressed down" is attested from 1650s. The meaning "dejection, state of sadness, a sinking of the spirits" is from early 15c. (as a clinical term in psychology, from 1905); meteorological sense is from 1881 (in reference to barometric pressure); meaning "a lowering or reduction in economic activity" was in use by 1826; given a specific application (with capital D-) by 1934 to the one that began worldwide in 1929. For "melancholy, depression" an Old English word was grevoushede.

A melancholy leading to desperation, and known to theologians under the name of 'acedia,' was not uncommon in monasteries, and most of the recorded instances of medieval suicides in Catholicism were by monks. [Lecky, "History of European Morals"]

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Definitions of depression
1
depression (n.)
a mental state characterized by a pessimistic sense of inadequacy and a despondent lack of activity;
depression (n.)
a long-term economic state characterized by unemployment and low prices and low levels of trade and investment;
Synonyms: slump / economic crisis
depression (n.)
a sunken or depressed geological formation;
Synonyms: natural depression
depression (n.)
sad feelings of gloom and inadequacy;
depression (n.)
an air mass of lower pressure; often brings precipitation;
Synonyms: low
depression (n.)
a state of depression and anhedonia so severe as to require clinical intervention;
Synonyms: depressive disorder / clinical depression
depression (n.)
a concavity in a surface produced by pressing;
Synonyms: impression / imprint
depression (n.)
angular distance below the horizon (especially of a celestial object);
depression (n.)
pushing down;
depression of the space bar on the typewriter
2
Depression (n.)
a period during the 1930s when there was a worldwide economic depression and mass unemployment;
Synonyms: Great Depression
From wordnet.princeton.edu