Etymology
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depletion (n.)

"act of emptying or reducing," 1650s, from Late Latin depletionem (nominative depletio) "blood-letting," noun of action from past-participle stem of Latin deplere "to empty," literally "to un-fill," from de "off, away" (see de-) + plere "to fill" (from PIE root *pele- (1) "to fill").

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Definitions of depletion

depletion (n.)
the act of decreasing something markedly;
depletion (n.)
the state of being depleted;
From wordnet.princeton.edu