"empty, reduce, or exhaust by drawing away," 1807, originally in medicine (of blood-letting, purgatives), back-formation from depletion, which is from Latin deplere "to empty," literally "to un-fill," from de "off, away" (see de-) + plere "to fill" (from PIE root *pele- (1) "to fill"). General sense by 1859. Related: Depleted; depleting.
updated on July 25, 2018
Dictionary entries near deplete