word-forming element meaning "against, in opposition," from Latin adverb and preposition contra "against" (see contra (prep., adv.)). The Latin word was used as a prefix in Late Latin. In French, it became contre- and passed into English as counter-. The Old English equivalent was wiðer (surviving in withers and widdershins), from wið "with, against."
1650s, "to point out," back-formation from indication (q.v.) or else from Latin indicatus, past participle of indicare "to point out, show," from in- "into, in, on, upon" (from PIE root *en "in") + dicare "proclaim" (from PIE root *deik- "to show," also "pronounce solemnly," and see diction). Especially "to give suggestion of, be reason for inferring" (1706). Related: Indicated; indicating.
<a href="https://www.etymonline.com/word/contra-indicate">Etymology of contra-indicate by etymonline</a>
Harper, D. (n.d.). Etymology of contra-indicate. Online Etymology Dictionary. Retrieved $(datetime), from https://www.etymonline.com/word/contra-indicate