Etymology
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bothersome (adj.)

"troublesome, annoying," 1817, from bother + -some (1).

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Definitions of bothersome

bothersome (adj.)
causing irritation or annoyance;
aircraft noise is particularly bothersome near the airport
Synonyms: annoying / galling / irritating / nettlesome / pesky / pestering / pestiferous / plaguy / plaguey / teasing / vexatious / vexing
From wordnet.princeton.edu

Dictionary entries near bothersome

botany

botch

both

bother

botheration

bothersome

botony

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botryo-

bottle

bottleneck