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botheration (n.)

"annoyance, petty vexation," 1788, noun of action from bother (v.).

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Definitions of botheration from WordNet

botheration (n.)
the psychological state of being irritated or annoyed;
botheration (n.)
something or someone that causes trouble; a source of unhappiness;
Synonyms: annoyance / bother / pain / infliction / pain in the neck / pain in the ass
From wordnet.princeton.edu

Dictionary entries near botheration

botanist

botany

botch

both

bother

botheration

bothersome

botony

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botryo-

bottle