asthenia (n.)

prefix meaning "not, without," from Greek a-, an- "not" (the "alpha privative"), from PIE root *ne- "not" (source also of English un-).

In words from Greek, such as abysmal, adamant, amethyst; also partly nativized as a prefix of negation (asexual, amoral, agnostic). The ancient alpha privatum, denoting want or absence.

Greek also had an alpha copulativum, a- or ha-, expressing union or likeness, which is the a- expressing "together" in acolyte, acoustic, Adelphi, etc. It is from PIE root *sem- (1) "one; as one, together with."

Proto-Indo-European root meaning "to hold."

It forms all or part of: Antioch; asseverate; asthenia; asthenosphere; cachectic; cachexia; calisthenics; cathexis; entelechy; eunuch; epoch; hectic; Hector; ischemia; myasthenia; neurasthenia; Ophiuchus; persevere; schema; schematic; scheme; scholar; scholastic; school (n.1) "place of instruction;" severe; severity; Siegfried.

It is the hypothetical source of/evidence for its existence is provided by: Sanskrit sahate "he masters, overcomes," sahah "power, victory;" Avestan hazah "power, victory;" Greek skhema "figure, appearance, the nature of a thing," related to skhein "to get," ekhein "to have, hold; be in a given state or condition;" Gothic sigis, Old High German sigu, Old Norse sigr, Old English sige "victory."