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antagonistic (adj.)

"acting in opposition," 1630s, from antagonist + -ic. Related: Antagonistical (1620s); antagonistically.

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Definitions of antagonistic from WordNet

antagonistic (adj.)
indicating opposition or resistance;
Synonyms: counter
antagonistic (adj.)
characterized by antagonism or antipathy;
slaves antagonistic to their masters
Synonyms: antipathetic / antipathetical
antagonistic (adj.)
arousing animosity or hostility;
his antagonistic brusqueness
Europe was antagonistic to the Unites States
antagonistic (adj.)
used especially of drugs or muscles that counteract or neutralize each other's effect;
Synonyms: incompatible
antagonistic (adj.)
incapable of harmonious association;
From wordnet.princeton.edu