12c., agenes "in opposition to, adverse, hostile; in an opposite direction or position, in contact with, in front of, so as to meet," originally a southern variant of agan (prep.) "again" (see again), with adverbial genitive. The unetymological -t turned up mid-14c. and was standard by early 16c., perhaps from influence of superlatives (see amidst). Use as a conjunction, "against the time that," hence "before," is now archaic or obsolete.
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