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signature (n.)

1530s, a kind of document in Scottish law, from French signature (16c.) or directly from Medieval Latin signatura "signature, a rescript," in classical Latin "the matrix of a seal," from signatus, past participle of signare "to mark with a stamp, sign" (see sign (v.)).

Meaning "one's own name written in one's own hand" is from 1570s, replacing sign-manual (early 15c.) in this sense. Musical sense of "signs placed it the beginning of a staff to indicate the key and rhythm" is from 1806. Meaning "a distinguishing mark of any kind" is from 1620s.

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Definitions of signature from WordNet

signature (n.)
your name written in your own handwriting;
signature (n.)
a distinguishing style;
Synonyms: touch
signature (n.)
a melody used to identify a performer or a dance band or radio/tv program;
Synonyms: signature tune / theme song
signature (n.)
the sharps or flats that follow the clef and indicate the key;
Synonyms: key signature
signature (n.)
a sheet with several pages printed on it; it folds to page size and is bound with other signatures to form a book;
From wordnet.princeton.edu