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quintessence (n.)

early 15c., in ancient and medieval philosophy, "pure essence, substance of which the heavenly bodies are composed," literally "fifth essence," from Old French quinte essence (14c.), from Medieval Latin quinta essentia, from Latin quinta, fem. of quintus "fifth" (from PIE root *penkwe- "five") + essentia "being, essence," abstract noun formed (to translate Greek ousia "being, essence") from essent-, present-participle stem of esse "to be" (from PIE root *es- "to be").

A loan-translation of Greek pempte ousia, the "ether" added by Aristotle to the four known elements (water, earth, fire, air) and said to permeate all things. Its extraction was one of the chief goals of alchemy. Sense of "purest essence" (of a situation, character, etc.) is first recorded 1580s.

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Definitions of quintessence from WordNet

quintessence (n.)
the fifth and highest element after air and earth and fire and water; was believed to be the substance composing all heavenly bodies;
Synonyms: ether
quintessence (n.)
the purest and most concentrated essence of something;
quintessence (n.)
the most typical example or representative of a type;
From wordnet.princeton.edu