1963, short for Papanicolaou (1947) in reference to George Nicholas Papanicolaou (1883-1962), Greek-born U.S. anatomist who developed the technique of examining secreted cells to test for cancer.
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Definitions of Pap test from WordNet
Pap test (n.)
a method of examining stained cells in a cervical smear for early diagnosis of uterine cancer;
