early 15c., "a breaking of a bone," from Old French fracture (14c.) and directly from Latin fractura "a breach, break, cleft," from fractus, past participle of frangere "to break" (from PIE root *bhreg- "to break"). As "a broken surface" from 1794.
"cause a fracture in" (transitive), 1610s (implied in fractured), from fracture (n.). Intransitive meaning "become fractured" is from 1830. Related: Fracturing.