fem. proper name, from Italian, literally "lady," from Latin domina "lady, mistress of the house," from Latin domus "house" (from PIE root *dem- "house, household"). A top 20 name for girls born in the U.S. from 1941 to 1967 (top 10 from 1955 to 1965).
"a lady," 1660s, from the common title of respect for Italian and Portuguese ladies, equivalent to Spanish doña, prefixed to the Christian name. The fem. equivalent of don (n.).