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Appalachia

"cultural and geographical region of inland Eastern U.S.," 1880s, from the Appalachian Mountains, which are its core. Earlier Appalachia was proposed as a better name for "United States of America" by Washington Irving in 1839 (though he preferred Alleghenia) and this may have been the coinage of the word (see America).

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Definitions of Appalachia from WordNet

Appalachia (n.)
an impoverished coal mining area in the Appalachian Mountains (from Pennsylvania to North Carolina);
From wordnet.princeton.edu