Etymology
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-sophy 
word-forming element meaning "knowledge," from Old French -sophie, from Latin -sophia, from Greek -sophia, from sophia "skill, wisdom, knowledge" (see Sophia).
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-dom 

abstract suffix of state, from Old English dom "statute, judgment" (see doom (n.)). Originally an independent word, but already active as a suffix in Old English (as in freodom, wisdom). Cognate with German -tum (Old High German tuom). "Jurisdiction," hence "province, state, condition, quality."

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ophio- 

before vowels ophi-, word-forming element meaning "a snake, serpent," from Greek ophio-, combining form of ophis "serpent, a snake," probably from PIE *egwhi- (source also of Sanskrit ahi-, Avestan aži- "snake," and perhaps the first element of a Germanic word for "lizard," i.e. Old High German egi-dehsa). Hence ophiolatry "serpent-worship" (1862), and the 2c. sect of the Ophitæ, who revered the serpent as the symbol of divine wisdom. 

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