"an opening, a mouth or aperture," early 15c., from Old French orifice "the opening of a wound" (14c.) and directly from Late Latin orificium "an opening," literally "mouth-making," from Latin os (genitive oris) "mouth" (see oral) + combining form of facere "to make, do" (from PIE root *dhe- "to set, put"). Related: Orificial.

"orifice of communication between the stomach and intestines," 1610s, from Late Latin pylorus "the lower orifice of the stomach," from Greek pylōros "lower orifice of the stomach," literally "gatekeeper, porter," from pylē "gate" (see pylon) + ouros "watcher, guardian" (from PIE root *wer- (3) "perceive, watch out for"). Related: Pyloric.

"canal through which urine is discharged from the bladder," 1630s, from Late Latin urethra, from Greek ourethra "the passage for urine," coined by Hippocrates from ourein "to urinate," from ouron (see urine). Related: Urethral.

"spasmodic narrowing of the orifice of the vagina," 1861, medical Latin, from vagina + -ismus (see -ism).

"surgical operation making a permanent opening in the body," 1957, abstracted from colostomy, etc.; ultimately from Modern Latin stoma "opening, orifice," from Greek stoma "mouth" (see stoma).

"having foul breath," 1889; from Greek sapros "putrid" (see sapro-) + stoma "orifice" (see stoma).

"contraction of the preputial orifice," 1670s, from Greek phimosis, literally "muzzling," from phimos "a muzzle, a gag," a word of unexplained etymology.

1610s, "to form into tubes," from in- (2) "in" + Latin tuba "tube" (see tuba) + -ate (2). Medical sense is from 1887. Related: Intubated. Intubation "act of inserting a tube" (into an orifice) is from 1885.

plural foramina, 1670s, from Latin foramen "hole, opening, aperture, orifice," from forare "to pierce" (from PIE root *bhorh- "hole").

1726, from tracheo-, used as a combining form of trachea + -ostomy "artificial opening," from Modern Latin stoma "opening, orifice," from Greek stoma "mouth" (see stoma).