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stir (n.)
"commotion, disturbance, tumult," late 14c. (in phrase on steir), probably from a Scandinavian source, such as Old Norse styrr "disturbance, tumult," from the same root as stir (v.)). The sense of "movement, bustle" (1560s) probably is from the English verb.
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stir (v.)
Old English styrian "to stir, move; rouse, agitate, incite, urge" (transitive and intransitive), from Proto-Germanic *sturjan (source also of Middle Dutch stoeren, Dutch storen "to disturb," Old High German storan "to scatter, destroy," German stören "to disturb"), from PIE *(s)twer- (1) "to turn, whirl" (see storm (n.)). Related: Stirred; stirring. Stir-fry (v.) is attested from 1959.
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up (n.)
"that which is up," 1530s, from up (adv.). Phrase on the up-(and-up) "honest, straightforward" first attested 1863, American English.
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up (adv.)

Old English up, uppe, from Proto-Germanic *upp- "up" (source also of Old Frisian, Old Saxon up "up, upward," Old Norse upp; Danish, Dutch op; Old High German uf, German auf "up"; Gothic iup "up, upward," uf "on, upon, under;" Old High German oba, German ob "over, above, on, upon"), from PIE root *upo "under," also "up from under," hence also "over."

As a preposition, "to a higher place" from c. 1500; also "along, through" (1510s), "toward" (1590s). Often used elliptically for go up, come up, rise up, etc. Up the river "in jail" first recorded 1891, originally in reference to Sing Sing, which is up the Hudson from New York City. To drive someone up the wall (1951) is from the notion of the behavior of lunatics or caged animals. Insulting retort up yours (scil. ass) is attested by late 19c.

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up- 
prefix with various senses, from Old English up (adv.), corresponding to similar prefixes in other Germanic languages.
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stir-crazy (adj.)
1908, from crazy (adj.) + stir (n.) "prison" (1851), probably from Start Newgate (1757), prison in London, later any prison (1823), probably from Romany stardo "imprisoned," related to staripen "a prison." According to Barnhart, mid-19c. sturaban, sturbin "state prison" seem to be transitional forms.
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up (v.)

1550s, "to drive and catch (swans)," from up (adv.). Intransitive meaning "get up, rise to one's feet" (as in up and leave) is recorded from 1640s. Sense of "to move upward" is recorded from 1737. Meaning "increase" (as in up the price of oil) is attested from 1915. Compare Old English verb uppian "to rise up, swell." Related: Upped; upping. Upping block, used for mounting or dismounting horses, carriages, etc., is attested from 1796 (earlier was horsing-block, 1660s).

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up (adj.)
c. 1300, "dwelling inland or upland," from up (adv.). Meaning "going up" is from 1784. From 1815 as "excited, exhilarated, happy," hence "enthusiastic, optimistic." Up-and-coming "promising" is from 1848. Musical up-tempo (adj.) is recorded from 1948.
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cover-up (n.)

also coverup, "means or act of concealing" some event or activity, 1922, from the verbal phrase (1872), from cover (v.) + up (adv.).

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pop-up (n.)
from 1906 as a type of baseball hit; from pop (v.) + up (adv.). As an adjective from 1934 (of a children's book, later toasters, etc.).
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