c. 1400, "actually, in fact, in a real manner," originally in reference to the presence of Christ in the Eucharist, "substantially," from real (adj.) + -ly (2). The general sense is from early 15c. Purely emphatic use dates from c. 1600, "indeed," sometimes as a corroboration, sometimes as an expression of surprise or a term of protest; interrogative use (as in oh, really?) is recorded from 1815.
mid-15c., "unfortunate event or circumstance," from mis- (1) "bad, wrong" + fortune. From c. 1500 as "adversity or ill fortune for which the sufferer is not directly responsible." In 19c., it was a euphemism for "illegitimate child." Related: Misfortunate.
Mischance is the lightest word for that which is really disagreeable; a mishap may be comparatively a trivial thing; both generally apply to the experience of individuals. Misfortune is the most general of these words; a misfortune is a really serious matter; it may befall a person, family, or nation. A very serious misfortune affecting large numbers is a calamity, the central idea of which is wide-spread and general mischief. [Century Dictionary, 1895]
"act or fact of standing in line," 1918, verbal noun from queue (v.).
"Queueing" had really become an equivalent for sport with some working-class women. It afforded an occasion and an opportunity for gossip. ["The War of Food in Britain," in The Congregationalist and Advance, April 25, 1918]