Etymology
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one (adj., pron., n.)

"being but a single unit or individual; being a single person, thing, etc. of the class mentioned;" as a pronoun, "a single person or thing, an individual, somebody;" as a noun, "the first or lowest of the cardinal numerals; single in kind, the same; the first whole number, consisting of a single unit; unity; the symbol representing one or unity;" c. 1200, from Old English an (adjective, pronoun, noun) "one," from Proto-Germanic *ainaz (source also of Old Norse einn, Danish een, Old Frisian an, Dutch een, German ein, Gothic ains), from PIE root *oi-no- "one, unique."

Originally pronounced as it still is in only, atone, alone, and in dialectal good 'un, young 'un, etc.; the now-standard pronunciation "wun" began c. 14c. in southwest and west England (Tyndale, a Gloucester man, spells it won in his Bible translation), and it began to be general 18c. Its use as indefinite pronoun was influenced by unrelated French on and Latin homo.

Before the name of a person, indicating "hitherto unknown" or not known to the speaker.

One and only "sweetheart" is from 1906. Slang one-arm bandit for a type of slot machine is recorded by 1938. One-night stand is 1880 in performance sense; 1963 in sexual sense. One of the boys "ordinary amiable fellow" is from 1893. One-track mind "mind capable of only one line of thought or action" is by 1915. Drinking expression one for the road is from 1950 (as a song title). One-man band is by 1909 in a literal sense, 1914 figurative. One of those things "unpredictable occurrence" is from 1934.

The conscience clause is one of the weaknesses of the Bill. It is one of those things which tend to create the bitterness. The conscience clause is one of those things which are inseparable from a Bill like this. It is one of those things which divides the sheep from the goats—members can pick them out for themselves—in the playground, in the school. ["Religious Exercises in School Bills," New Zealand Parliamentary Debates, Aug. 13, 1926]
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-one 
chemical suffix, from Greek -one, female patronymic (as in anemone, "daughter of the wind," from anemos); in chemical use denoting a "weaker" derivative. Its use in forming acetone (1830s) gave rise to the specialized chemical sense.
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up (n.)
"that which is up," 1530s, from up (adv.). Phrase on the up-(and-up) "honest, straightforward" first attested 1863, American English.
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up (adv.)

Old English up, uppe, from Proto-Germanic *upp- "up" (source also of Old Frisian, Old Saxon up "up, upward," Old Norse upp; Danish, Dutch op; Old High German uf, German auf "up"; Gothic iup "up, upward," uf "on, upon, under;" Old High German oba, German ob "over, above, on, upon"), from PIE root *upo "under," also "up from under," hence also "over."

As a preposition, "to a higher place" from c. 1500; also "along, through" (1510s), "toward" (1590s). Often used elliptically for go up, come up, rise up, etc. Up the river "in jail" first recorded 1891, originally in reference to Sing Sing, which is up the Hudson from New York City. To drive someone up the wall (1951) is from the notion of the behavior of lunatics or caged animals. Insulting retort up yours (scil. ass) is attested by late 19c.

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up- 
prefix with various senses, from Old English up (adv.), corresponding to similar prefixes in other Germanic languages.
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up (v.)

1550s, "to drive and catch (swans)," from up (adv.). Intransitive meaning "get up, rise to one's feet" (as in up and leave) is recorded from 1640s. Sense of "to move upward" is recorded from 1737. Meaning "increase" (as in up the price of oil) is attested from 1915. Compare Old English verb uppian "to rise up, swell." Related: Upped; upping. Upping block, used for mounting or dismounting horses, carriages, etc., is attested from 1796 (earlier was horsing-block, 1660s).

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up (adj.)
c. 1300, "dwelling inland or upland," from up (adv.). Meaning "going up" is from 1784. From 1815 as "excited, exhilarated, happy," hence "enthusiastic, optimistic." Up-and-coming "promising" is from 1848. Musical up-tempo (adj.) is recorded from 1948.
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one-sided (adj.)

1833, "dealing with one side only of a question or dispute," hence, "partial, unjust, unfair," from one + side (n.). Translating German ein-seitiger. Related: One-sidedly; one-sidedness.

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one-time (adj.)

"that was, former," by 1850, from one + time (n.).

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one-liner (n.)

"short joke, witty remark," by 1951, from one + line.

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