word-forming element meaning "middle," used as a combining form of Latin medius "in the middle, between; from the middle," from PIE root *medhyo- "middle."
word-forming element meaning "process of measuring," Middle English -metrie, from French -metrie, from Latin -metria, from Greek -metria "a measuring of," from -metros "measurer of," from metron "measure," from PIE root *me- (2) "to measure."
derivational suffix, also -le, used mostly with verbs but originally also with nouns, "often denoting diminutive, repetitive, or intensive actions or events" [The Middle English Compendium], from Old English. Compare brastlian alongside berstan (see burst); nestlian (see nestle) alongside nistan). It is likely also in wrestle, trample, draggle, struggle, twinkle, also noddle "to make frequent nods" (1733). New formations in Middle English might be native formations (jostle from joust) with this or borrowings from Dutch.