Etymology
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meddle (v.)

early 14c., "to mingle, blend, mix" (a sense now obsolete), from Old North French medler (Old French mesler, 12c., Modern French mêler) "to mix, mingle, to meddle," from Vulgar Latin *misculare (source of Provençal mesclar, Spanish mezclar, Italian mescolare, meschiare), from Latin miscere "to mix" (from PIE root *meik- "to mix").

From late 14c. as "busy oneself, be concerned with, engage in," and in the disparaging sense of "interfere or take part in inappropriately or impertinently, be officious, make a nuisance of oneself" (the notion is of meddling too much), which is the surviving sense of the word. From mid-14c. to c. 1700 it also was a euphemism for "have sexual intercourse." Related: Meddled; meddling.

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meddling (n.)

mid-14c., "action of blending," verbal noun from meddle (v.). Meaning "act or habit of interfering in matters not of one's proper concern" is from late 14c. As a present-participle adjective, from 1520s. Related: Meddlingly.

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meddler (n.)

late 14c., "practitioner," agent noun from meddle (v.). Meaning "one who interferes with things in which he has no personal or proper concern, a nuisance" is mid-15c.

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mell (v.)

"to mix, blend, meddle," now obsolete or provincial, c. 1300, mellen, from Old French meller, variant of mesler (see meddle). Related: Melled; melling.

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melange (n.)

"a mixture, a medley," usually "an uncombined mingling on elements, objects, or individuals," 1650s, from French mélange (15c.), from mêler "to mix, mingle," from Old French mesler "to mix, meddle, mingle" (see meddle).

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intermeddle (v.)
late 14c., entremedlen, "to mix together, blend," from Anglo-French entremedler, Old French entremesler; from inter- + Anglo-French medler (see meddle (v.)). From early 15c. as "involve oneself in what is not one's business."
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pell-mell (adv.)

"confusedly; in an impetuous rush; with indiscriminate violence, energy, or eagerness," 1570s, from French pêle-mêle, from Old French pesle mesle (12c.), apparently a jingling rhyme on the second element, which is from the stem of the verb mesler "to mix, mingle" (see meddle). The phonetic form pelly melly is attested in English from mid-15c.

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melee (n.)

"confused conflict among many persons," 1640s, from French mêlée, from Old French meslee "brawl, confused fight; mixture, blend" (12c.), noun use of fem. past participle of mesler "to mix, mingle" (see meddle). See also medley. Borrowed in Middle English as melle but it was lost and then reborrowed 17c.

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medley (n.)

c. 1300, "hand-to-hand combat, war, battle," a sense now obsolete, from Old French medlee, variant of meslee, from mesler "to mix, mingle, meddle" (see meddle). From mid-14c. as "cloth made of wools dyed and mingled before being spun," whether of one color or many, but especially pied cloth. The general meaning "a combination, a mixture" is from c. 1400; that of "musical composition or entertainment consisting of diverse parts from different sources" is from 1620s.

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meddlesome (adj.)

"given to meddling, apt to interpose in the affairs of others," 1610s, from meddle + -some (1). Earlier was medlous "quarrelsome, meddlesome" (mid-15c.). Related: Meddlesomely; meddlesomeness. "Meddlesome Matty" is the title of a piece by Ann Taylor in "Original Poems for Infant Minds" (1806) about a little girl who, by meddling, breaks her grandmother's eye-glasses and gets a face-full of grandma's snuff.

Matilda, smarting with the pain,
  And tingling still, and sore,
Made many a promise to refrain
  From meddling evermore;
And 'tis a fact as I have heard.
She ever since has kept her word.

The book, which also included "Twinkle, Twinkle, Little Star" by Ann's sister Jane, was very popular in its day.

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