Etymology
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leper (n.)
"one afflicted with leprosy," late 14c., earlier "the disease leprosy," from Late Latin lepra, from Greek lepra "leprosy," noun use of fem. of lepros (adj.) "scaly, scabby, rough, leprous," related to lepein "to peel," from lepos, lepis "a scale," from PIE root *lep- (1) "to peel," which also yields words for "something delicate and weak," via the notion of "small shaving, flake, scale" (cognates: Latin lepidus "pleasant, charming, fine, elegant, effeminate," lepos "pleasantness, agreeableness;" Old English læfer "rush, reed; metal plate;" Lithuanian lopas "patch, rag, cloth," lepus "soft, weak, effeminate").

Originally in Middle English this was the word for the disease itself (mid-13c., via Old French lepre); the shift in meaning to "person with leprosy" perhaps developed in Anglo-French, or is because the -er ending resembled an agent-noun affix. By mid-15c. other nouns for the disease were being coined (see leprosy). In English lepra also was an old name for psoriasis (late 14c.).
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leprophilia (n.)
"strong abnormal attraction to people with leprosy," 1959 (Graham Greene), from combining form of leper (q.v.) + -philia. Related: Leprophil. Leprophobia is from 1888.
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leprous (adj.)
"infected with leprosy," early 13c., leprus, from Old French lepros (Modern French lépreux), from Late Latin leprosus, from Latin lepra "leprosy" (see leper).
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laparoscopy (n.)
1855, from -scopy + combining form of Greek lapara "flank, loins, soft part of the body between the ribs and the hips," from laparos "soft, slack, loose," from PIE *lap-aro-, suffixed form of root *lep- (1) "to peel" (see leper). Related: Laparoscopic; laparoscope.
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lepido- 
before vowels lepid-, word-forming element used since late 18c. in science with a sense of "scale" (of a fish, etc.), combining form of Greek lepis (genitive lepidos) "scale of a fish" (related to lepein "to peel;" see leper). As in lepidodendron (1819 in German), common fossil "club-moss tree" of the Carboniferous.
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lepton (n.)
elementary particle of small mass, 1948, from Greek leptos "small, slight, slender, delicate, subtle," literally "peeled," or "threshed out" (from lepein "to peel," from PIE *lep- (1), a root which yields words for "peel" as well as "small shaving, scale (of a fish)," hence used of things fine, delicate, or weak; see leper) + -on. In Greek it was the name of a small coin, from neuter of leptos. Related: Leptonic.
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leprosy (n.)

name given to various chronic skin diseases, later in more restricted use, 1530s, probably from leprous + -y (4). First used in Coverdale Bible, where it renders Hebrew cara'ath, which apparently was a comprehensive term for skin diseases. Also known as Hansen's disease (1938) for Norwegian physician Gerhard Henrik Armauer Hansen (1841-1912) who in 1871 discovered the bacillus that causes it.

The Middle English name for the disease was leper (mid-13c.), from Old French liepre and Latin lepra (see leper). But as the sense of this shifted after late 14c. to mean "person with leprosy," English began coining new nouns for the disease: lepri, leprosity, lepruse all date from mid-15c. but are now obsolete. A place for their treatment is a leprosarium (1846) or leprosary (1869, from French).

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lazar (n.)
"filthy beggar, leper," c. 1300, from Medieval Latin lazarus "leper," from Lazarus (q.v.), the name of the beggar in the biblical parable. Sometimes also lazard, with pejorative suffix.
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lazzarone (n.)
"Italian beggar," 1792, Italian, augmentative of lazzaro "a beggar, leper," from Lazarus (q.v.).
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mesel 

"leprous" (adj.); "a leper" (n.); both c. 1300, from Old French mesel "wretched, leprous; a wretch," from Latin misellus "wretched, unfortunate," as a noun, "a wretch," in Medieval Latin, "a leper," diminutive of miser "wretched, unfortunate, miserable" (see miser). A Latin diminutive form without diminutive force. Also from Latin misellus are Old Italian misello "sick, leprous," Catalan mesell "sick." The English word is archaic or obsolete since the 1500s, replaced by leper, leprous, but its lexical DNA survives, apparently, as a contamination of measles.

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