c. 1300, from Old French ire "anger, wrath, violence" (11c.), from Latin ira "anger, wrath, rage, passion," from PIE root *eis- (1), forming various words denoting passion (source also of Greek hieros "filled with the divine, holy," oistros "gadfly," originally "thing causing madness;" Sanskrit esati "drives on," yasati "boils;" Avestan aesma "anger;" Lithuanian aistra "violent passion").

Old English irre in a similar sense is unrelated; it is from an adjective irre "wandering, straying, angry," which is cognate with Old Saxon irri "angry," Old High German irri "wandering, deranged," also "angry;" Gothic airzeis "astray," and Latin errare "wander, go astray, angry" (see err (v.)).

"expounder of sacred mysteries," 1670s, from Late Latin hierophantes, from Greek hierophantes "one who teaches the rites of sacrifice and worship," literally "one who shows sacred things," from hieros "sacred," from PIE root *eis-, forming words denoting passion (see ire) + phainein "to reveal, bring to light" (from PIE root *bha- (1) "to shine"). In modern use, "expounder of esoteric doctrines," from 1822.

"angry, inclined to wrath," 1707, from Late Latin iracundus, from ira "anger, wrath, rage, passion" (see ire (n.)). Related: Iracundulous (1765).

[T]he Severn is so mischievous and cholerick a river, and so often ruins the country with sudden inundations, since it rises in Wales, and consequently participates sometimes of the nature of that hasty, iracund people among whom 'tis born. [Thomas Browne, "Letters from the Dead to the Living," 1707]