Etymology
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inure (v.)
formerly also enure, mid-15c., "accustom, adapt, establish by use," contracted from phrase (put) in ure "in practice" (early 15c.), from obsolete noun ure "work, practice, exercise, use," probably from Old French uevre, oeuvre "work," from Latin opera "work" (from PIE root *op- "to work, produce in abundance"). Meaning "toughen or harden by experience" is from late 15c. Related: Inured; inuring.
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*op- 

Proto-Indo-European root meaning "to work, produce in abundance."

It forms all or part of: cooperate; cooperation; copious; copy; cornucopia; hors d'oeuvre; inure; maneuver; manure; oeuvre; office; official; officinal; omni-; omnibus; omnium gatherum; op. cit.; opera; operate; operation; operose; optimism; optimum; opulence; opulent; opus; Oscan.

It is the hypothetical source of/evidence for its existence is provided by: Sanskrit apas- "work, religious act," apnas- "possession, property;" Hittite happina- "rich;" Avestan huapah- "doing good work, masterly;" Latin opus "a work, labor, exertion;" Greek ompne "food, corn;" Old High German uoben "to start work, to practice, to honor;" German üben "to exercise, practice;" Dutch oefenen, Old Norse æfa, Danish øve "to exercise, practice;" Old English æfnan "to perform, work, do," afol "power."

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acclimatize (v.)

1824, "modify a living thing to suit a foreign climate" (transitive); see acclimate + -ize. A more recent formation than acclimate and generally replacing it in this sense. Related: Acclimatized; acclimatizing. Simple climatize is attested from 1826 as "inure (a living thing) to a climate."

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